Metformin hydrochloride, also known as Glucophage, is a medication primarily used to treat type 2 diabetes. It belongs to the biguanide class of medications and works by reducing glucose production in the liver and increasing insulin sensitivity.
It is available in various forms, including tablets, oral solutions, and extended-release tablets. Metformin hydrochloride has been widely prescribed for over three decades due to its effectiveness and relatively low risk of adverse effects compared to other diabetes treatments.
Metformin hydrochloride works by reducing glucose production in the liver and increasing insulin sensitivity. This is achieved through several mechanisms, including:
- Reducing glucose absorption in the gut
- Increasing glucose excretion in the urine
- Enhancing insulin-mediated glucose uptake in muscles
While metformin hydrochloride has been widely prescribed for type 2 diabetes treatment, it is essential to discuss its benefits and risks. On the positive side:
- It has been shown to be effective in reducing HbA1c levels and improving glycemic control
- It can also help with weight loss and improve cardiovascular outcomes